Below please find details on our past 5 years of research funding. If you are interested in learning more about past MOCA research funding, please call the MOCA office at 612-822-0500.

2019 MOCA Research Funding

MOCA awarded $680,000 in funding to researchers in Minnesota and across the nation. In addition to the 2019 funding awards, MOCA provided $475,000 to multi-year grant awards that were funded in 2017 and 2018.

The 2019 MOCA-funded researchers include:

• Melissa Geller, M.D., M.S., University of Minnesota. “IL-15 superagonist ALT 803 maintenance therapy to prevent recurrence of advanced stage ovarian cancer.” $100,000 for one year.
• XInyan Wu, Ph.D., Mayo Clinic. “A humanized antibody against AXL receptor tyrosine kinase as a novel therapy for ovarian cancer.” $100,000 for one year.
• Emil Lou, M.D., Ph.D., University of Minnesota. “Targeting channels of ovarian tumor cell communication.” $80,000 for one year.
• Valentina Zanfagnin, M.D., Mayo Clinic. “Repurposing ceritinib to enhance the efficacy of Olaparib in ovarian cancer.” $100,000 for one year.
• Reuben Harris, Ph.D. University of Minnesota. “Diagnosing and targeting APOBEC3B in clear cell ovarian carcinoma.” $100,000 for one year.
• Amy Skubitz, Ph.D., University of Minnesota. “Verification of a biomarker panel for the early detection of ovarian cancer using serum samples from multiple sources.” $150,000 for one year.
• Naoko Sasamoto, M.D., M.P.H., Brigham and Women’s Hospital, Boston, MA. “High throughput protemics profiling for identification of early detection biomarkers of high-grade serous ovarian cancer.” National Early Detection Research Grant Award. $50,000 for one year.

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2018 MOCA Research Funding

In May 2018, MOCA provided a total of $775,000 to ovarian cancer researchers. We awarded $675,000 to five ovarian cancer research projects developed by Minnesota researchers.

We also awarded $100,000 to two researchers as part of our National Early Detection Research Awards.

The 2018 MOCA-funded researchers include:

2018 Minnesota Research Projects: 

• Martina Bazzaro, Ph.D. University of Minnesota. “Targeting of mitochondrial activity to prevent and treat recurrent ovarian cancer.” $75,000 for one year. Spin it Teal Research Award.
• Carol Lange, Ph.D. and Laura Mauro, Ph.D. University of Minnesota. “Targeting DNA damage sensing protein kinases in hereditary ovarian cancer. $200,000 for two years.
• Swayam Prabha, Ph.D., MBA. University of Minnesota. “Glycoengineered mesenchymal stem cells for combination chemo and immunotherapy of ovarian cancer. $100,000 for one year.
• Viji Shridhar, Ph.D. Mayo Clinic. “Targeting LRRC15 to inhibit metastasis and recurrence of ovarian cancer.” $200,000 for two years.
• Bruce Walcheck, Ph.D. University of Minnesota. “Engineered natural killer cells expressing chimeric CD64 as a cancer immunotherapy.” $100,000 for one year.

2018 National Early Detection Research Awards: 

• Robert Bast, M.D. M.D. Anderson. “Serum autoantibodies for detection of early-stage ovarian cancer.” $50,000 for one year.
• Haiwei Gu, Ph.D. Arizona State University. “Metabolomics diagnosis of ovarian cancer.” $50,000 for one year.

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2017 MOCA Research Funding

In May 2017, MOCA awarded $775,000 to ovarian cancer researchers from the University of Minnesota and Mayo Clinic.

The 2017 funded researchers included:

• Rachel Hurley, M.D., Ph.D. Candidate, Mayo Clinic. “Identifying novel therapeutic options for women with PARP inhibitor resistant ovarian cancer.” $50,000 for one year.
• Aminah Jatoi, M.D., Mayo Clinic. “A phase 2 trial of auranofin and sirolimus for recurrent ovarian cancer.” $150,000 over three years.
• Amy Skubitz, Ph.D., University of Minnesota. “Validation of biomarkers for the early detection of ovarian cancer.” $200,000 over two years.
• Swayam Prabha, Ph.D., MBA, University of Minnesota. “Translational studies on glycoengineered mesenchymal stem cells in ovarian cancer.”  $100,000 for one year.
• Andrea Wahner-Hendrickson, M.D., Mayo Clinic. ” PLK4 inhibition as a treatment strategy in high grade serous ovarian cancer” $275,000 over three years.

In November 2017, MOCA expanded our research funding beyond Minnesota with our first-ever National Early Detection Research Grant Awards.

After a rigorous national competitive grantmaking process, MOCA awarded $100,000 to two national research projects focused on early detection.

• Kevin Elias, M.D., from Brigham and Women’s Hospital in Boston, was awarded $50,000 for a one-year project focused on a blood test that is being tested as an early detection screening test of ovarian cancer.
• Barbara Norquist, M.D., from the University of Washington, Seattle was also awarded $50,000 for a one-year project focused on detecting ovarian cancer by uterine lavage with Crispr-duplex sequencing.

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2016 MOCA Research Funding

In May 2016, MOCA awarded $1,035,000 to ovarian cancer researchers at the University of Minnesota and Mayo Clinic.

The 2016 funded researchers included:

• Daniel Vallera, Ph.D., University of Minnesota. “Engaging the immune system to attack ovarian cancer.” $96,908.00
• Evanthia Galanis, M.D., Mayo Clinic. “Mesenchymal stem cell delivery of measles virus for recurrent ovarian cancer.” $89,636.00
• Amy Skubitz, Ph.D., University of Minnesota. “New platform for multiplexing biomarkers for the early detection of ovarian cancer.” $100,000.00
• Marina Walther-Antonio, Ph.D., Mayo Clinic. “Ovarian cancer microbiome signatures.” $98,335.00
• Melissa Geller, M.D., M.S. University of Minnesota. “IL-15 superagonist ALT-803 for treatment of advanced staged ovarian cancer.” $100,000.00
• Swayam Prabha, Ph.D., MBA. University of Minnesota. “Glycoengineered mesenchymal stem cells for targeting platinum resistant ovarian tumors.” $100,000.00
• Martina Bazzaro, Ph.D., University of Minnesota. “Breaking off cancer cells’ addictions to prevent and treat recurrent ovarian cancer.” $99,786.00
• Kimberly Kalli, Ph.D., Mayo Clinic. “Identification of ovarian cancer stromal and stem cell antigens as targets for immunotherapy designed to prevent ovarian cancer recurrence.” $70,000.
• William Cliby, M.D., Mayo Clinic. “Investigating the stromal contribution to the mesenchymal subtype of ovarian cancer for therapeutic potential.” $70,000.
• Cheryl Conover, Ph.D. and John Weroha, M.D., Ph.D., Mayo Clinic. “PAPP-A: A novel target for chemo-resistant ovarian cancer.” $99,959.00
• Reuben Harris, Ph.D. and Daniel Harki, Ph.D. University of Minnesota. “Stopping enzyme-catalyzed ovarian cancer evolution.” $81,309.00

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2015 MOCA Research Funding

At MOCA’s Annual Meeting in May 2015, our organization provided $660,000 to research projects based at the University of Minnesota and Mayo Clinic.

MOCA also branched out to national research funding for the first time in 2015, with $25,000 directed towards the Stand Up To Cancer (SU2C) Ovarian Cancer Dream Team funding, which MOCA has made a $100,000 commitment to be paid out over four years.

The 2015 research projects include:

• Reuben S. Harris, Ph.D., University of Minnesota. “Stopping Enzyme-Catalyzed Ovarian Cancer Evolution.” $100,000
• Ellen L. Goode, Ph.D., M.P.H., Mayo Clinic. “Pharmacogenomics, DNA repair and response to platinum and taxanes in epithelial ovarian cancer.” $97,040
• Swayam Prabha, Ph.D., M.B.A., University of Minnesota. “Glycoengineered mesenchymal stem cells as theranostic agents.”
• Andrea Wahner Hendrickson, M.D., Mayo Clinic. “Targeting platinum resistant ovarian cancer via MTH1 inhibition.” $85,000
• William Cliby, M.D., Mayo Clinic. “Targeting the TCFb signaling pathway for control of metastasis and fibrosis in ovarian cancer.” $80,803
• Carol A. Lange, Ph.D., University of Minnesota. “BRCA deficiency drives an enriched sex steroid milieu that supports hereditary ovarian cancer carcinogenesis.” $100,000.
• Daniel A. Vallera, Ph.D., University of Minnesota. “A novel anti-cancer stem cell drug for treating ovarian cancer.” $100,000